“Los Angeles” is the story of Jojo, a young mute, who thinks she hears God calling her to save the Baby Jesus. She packs five angels in a shoe shine kit and takes a one-way trip to Tampa, Florida, where she is picked up by Cash, an escaped convict. The two hit the road with the FBI on their tail. At different cities along the way, Jojo opens her shine kit, and the angels perform. Will Cash get to freedom? Will Jojo save the Baby Jesus? God only knows.

The owner of a small-town junkyard offers a cash reward to whomever can kill her uninvited, space-suited alien guest when its spacecraft crash-lands into her barn. Every wacko within 100 miles turns out, and before long, the junkyard is transformed into a war zone of man vs. man vs. machine vs. alien vs. God only knows what.